|
Symbol Name ID |
Pax6
paired box 6 MGI:97490 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Optic nerve hypoplasia |
Ventriculomegaly |
| Disease(s) Associated with PAX6 | ||
| bilateral optic nerve hypoplasia | ||
| coloboma |
| Mouse Phenotypes | nervous system phenotype |
abnormal neuron differentiation |
abnormal brain morphology |
abnormal brain development |
abnormal forebrain development |
abnormal telencephalon development |
thin cortical plate |
abnormal cortical ventricular zone morphology |
abnormal pallium development |
abnormal cerebellum external granule cell layer morphology |
abnormal brain commissure morphology |
abnormal brain internal capsule morphology |
abnormal pretectal region morphology |
abnormal forebrain morphology |
abnormal diencephalon morphology |
small thalamus |
abnormal telencephalon morphology |
abnormal cerebral cortex morphology |
thin cerebral cortex |
absent olfactory bulb |
telencephalon hypoplasia |
abnormal cerebellum morphology |
ectopic Purkinje cell |
abnormal cerebellar granule cell morphology |
abnormal cerebellum vermis morphology |
abnormal postnatal subventricular zone morphology |
abnormal embryonic/fetal subventricular zone morphology |
exencephaly |
absent amacrine cells |
abnormal ventral interneuron morphology |
abnormal ventral interneuron 0 morphology |
abnormal ventral interneuron 1 morphology |
abnormal ventral interneuron 3 morphology |
abnormal olfactory nerve morphology |
abnormal optic nerve morphology |
optic nerve degeneration |
optic nerve hypoplasia |
abnormal neuron physiology |
abnormal synaptic transmission |
abnormal CNS synaptic transmission |
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| Availability | Mouse Genotype | ||||||||||||||||||||||||||||||||||||||||
| Pax64Neu/Pax64Neu | |||||||||||||||||||||||||||||||||||||||||
| Pax6Mhdaaey18/Pax6Mhdaaey18 | |||||||||||||||||||||||||||||||||||||||||
| Pax6Sey-Neu/Pax6Sey-Neu | |||||||||||||||||||||||||||||||||||||||||
| Pax6Sey/Pax6Sey | |||||||||||||||||||||||||||||||||||||||||
| Pax6tm1.1Ued/Pax6tm1.1Ued | |||||||||||||||||||||||||||||||||||||||||
| Pax6tm1Gfs/Pax6tm1Gfs | * | ||||||||||||||||||||||||||||||||||||||||
| Pax6tm1Pgr/Pax6tm1Pgr | |||||||||||||||||||||||||||||||||||||||||
| Pax63Neu/Pax6+ | |||||||||||||||||||||||||||||||||||||||||
| Pax6em1(IMPC)Mbp/Pax6+ | |||||||||||||||||||||||||||||||||||||||||
| Pax6Sey-2H/Pax6+ | |||||||||||||||||||||||||||||||||||||||||
| Pax6Sey-Dey/Pax6+ | |||||||||||||||||||||||||||||||||||||||||
| Pax6Sey/Pax6+ | |||||||||||||||||||||||||||||||||||||||||
| Pax6tm1.1Zkoz/Pax6tm1.1Zkoz Tg(Rax-cre)1Zkoz/0 (conditional) |
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| Pax6tm1Ued/Pax6tm1Ued Tg(Six3-cre)69Frty/0 (conditional) |
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| Pax6tm2Pgr/Pax6+ Tg(Pax6-cre,GFP)1Pgr/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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